Complete prevalence and indicators of cancer cure: enhanced methods and validation in Italian population-based cancer registries

ABSTRACT:

Objectives

To describe the procedures to derive complete prevalence and several indicators of cancer cure from population-based cancer registries.

Materials and methods

Cancer registry data (47% of the Italian population) were used to calculate limited duration prevalence for 62 cancer types by sex and registry. The incidence and survival models, needed to calculate the completeness index (R) and complete prevalence, were evaluated by likelihood ratio tests and by visual comparison. A sensitivity analysis was conducted to explore the effect on the complete prevalence of using different R indexes. Mixture cure models were used to estimate net survival (NS); life expectancy of fatal (LEF) cases; cure fraction (CF); time to cure (TTC); cure prevalence, prevalent patients who

SUBMITTER: Toffolutti F 

PROVIDER: S-EPMC10280813 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature