Long-term follow-up and exploration of the mechanism of stromal vascular fraction gel in chronic wounds.

ABSTRACT:

Background

Chronic refractory wounds easily relapse and seriously affect the patients' quality of life. Previous studies have shown that stromal vascular fraction gel (SVF-gel) significantly promotes the early healing of chronic wounds; however, the mechanisms of SVF-gel function per se remain unclear, and a long-term follow-up is lacking. This study aims to explore the mechanisms of SVF-gel promoting the healing of chronic wounds and follow up the long-term efficacy of SVF-gel.

Methods

Autologous SVF-gel transplantation was performed in 20 patients with chronic wounds (from March 2016 to September 2019), and the size of the wound before and after SVF-gel transplantation was observed. The conditioned medium (CM) was harvested from SVF-gel under serum-free, serum-deprivation

SUBMITTER: Cai Y 

PROVIDER: S-EPMC10280847 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature