The Role of Defensins as Pollen and Food Allergens.

ABSTRACT:

Purpose of review

Defensin-polyproline-linked proteins are relevant allergens in Asteraceae pollen. Depending on their prevalence and amount in the pollen source, they are potent allergens, as shown for the major mugwort pollen allergen Art v 1. Only a few allergenic defensins have been identified in plant foods, such as peanut and celery. This review provides an overview of structural and immunological features, IgE cross-reactivity, and diagnostic and therapeutic options regarding allergenic defensins.

Recent findings

We present and critically review the allergenic relevance of pollen and food defensins. The recently identified Api g 7 from celeriac and other allergens potentially involved in Artemisia pollen-related food allergies are discussed and related to clinical sev

SUBMITTER: Cosi V 

PROVIDER: S-EPMC10281898 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature