Invasive Mold Infections in Children: Navigating Troubled Waters with a Broken Compass.

ABSTRACT: Incidence of invasive mold infections in children, while rare, is increasing as the population of high-risk patients expands, including premature infants, pediatric patients undergoing treatment for hematological malignancies, or recipients of allogeneic hematologic stem cell transplants. The infectious agents, including Aspergillus spp., Mucorales, and other molds, are especially difficult to treat and have serious morbidity and high mortality. Clinicians must maintain a high index of suspicion for invasive mold infections in at-risk patients. Diagnosis of invasive mold infections is complicated by difficulties isolating pathogens on culture, but progress is being made in immunological and molecular diagnostic technologies. Treatment in children is challenging; no randomized controlled tr

SUBMITTER: Arrieta AC 

PROVIDER: S-EPMC10281928 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature