The effect of burst suppression on cerebral blood flow and autoregulation: a scoping review of the human and animal literature.

ABSTRACT: Background: Burst suppression (BS) is an electroencephalography (EEG) pattern in which there are isoelectric periods interspersed with bursts of cortical activity. Targeting BS through anaesthetic administration is used as a tool in the neuro-intensive care unit but its relationship with cerebral blood flow (CBF) and cerebral autoregulation (CA) is unclear. We performed a systematic scoping review investigating the effect of BS on CBF and CA in animals and humans. Methods: We searched MEDLINE, BIOSIS, EMBASE, SCOPUS and Cochrane library from inception to August 2022. The data that were collected included study population, methods to induce and measure BS, and the effect on CBF and CA. Results: Overall, there were 66 studies that were included in the final results, 41 o

SUBMITTER: Siddiqi AZ 

PROVIDER: S-EPMC10282505 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature