Cr(vi) permanently binds to the lipid bilayer in an inverted hexagonal phase throughout the reduction process.

ABSTRACT: Cr(vi) is a harmful, carcinogenic agent with a high permeability rate throughout the lipid membranes. In an intracellular environment and during interactions with cellular membranes, it undergoes an instant reduction to lower oxidation states throughout radical states, recognized as the most dangerous factor for cells. The cellular membrane is the most visible cellular organelle in the interior and exterior of a cell. In this study, liposomes and non-lamellar inverted hexagonal phase lipid structures based on phosphoethanolamine (PE) were used as model cellular bilayers because of their simple composition, preparation procedure, and the many other properties of natural systems. The lipid membranes were subjected to 0.075 mM Cr(vi) for 15 min, after which the Cr content was removed via</

SUBMITTER: Nowakowski M 

PROVIDER: S-EPMC10282592 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature