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Monocyte at diagnosis as a prognosis biomarker in tuberculosis patients with anemia.


ABSTRACT:

Background

Anemia leads to a lower cure rate and poor prognosis in tuberculosis patients. Effective predictors for the prognosis of tuberculosis with anemia (A-TB) are urgently needed. Monocyte has been proven to be a prognostic biomarker of many lung diseases. Whether monocyte that the predominant innate immune cell as early defense against tuberculosis can predict A-TB is not known.

Methods

Data for A-TB patients with initial treatment in Shanghai Pulmonary Hospital were retrospectively collected and analyzed. Logistics regression analysis was used to study the correlation between peripheral blood cells and treatment outcomes. The receiver operating characteristic (ROC) curve was used to determine the cut-off value. We estimated a 12-month prognosis using Kaplan-Meier tech

SUBMITTER: Luo M 

PROVIDER: S-EPMC10282774 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature