Characterization of a Diverse Collection of Salmonella Phages Isolated from Tennessee Wastewater.

ABSTRACT:

Background

Salmonella enterica is one of the most prevalent bacterial foodborne pathogens. Salmonella phages are currently used in biocontrol applications and have potential for use as therapeutics.

Materials and methods

Phages were enriched and purified from a diversity of Salmonella host isolates. Morphology was determined with transmission electron microscopy, host ranges were characterized using an efficiency of plaquing assay, and comparative genomic analysis was performed to determine taxonomy.

Results

Ten phages were isolated and characterized. Phages showed activity against 23 out of the 24 Salmonella serovars evaluated. Two phages also showed activity against Escherichia coli strain B. Phages belonged to five different gener

SUBMITTER: Bryan DW 

PROVIDER: S-EPMC10282790 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature