Recent Vitamin K Antagonist Use and Intracranial Hemorrhage After Endovascular Thrombectomy for Acute Ischemic Stroke.

ABSTRACT:

Importance

Use of oral vitamin K antagonists (VKAs) may place patients undergoing endovascular thrombectomy (EVT) for acute ischemic stroke caused by large vessel occlusion at increased risk of complications.

Objective

To determine the association between recent use of a VKA and outcomes among patients selected to undergo EVT in clinical practice.

Design, setting, and participants

Retrospective, observational cohort study based on the American Heart Association's Get With the Guidelines-Stroke Program between October 2015 and March 2020. From 594 participating hospitals in the US, 32 715 patients with acute ischemic stroke selected to undergo EVT within 6 hours of time last known to be well were included.

Exposure

VKA use within the 7 days prior to hospital arr

SUBMITTER: Mac Grory B 

PROVIDER: S-EPMC10282891 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature