Ontology highlight
ABSTRACT:
SUBMITTER: Lee BN
PROVIDER: S-EPMC10283147 | biostudies-literature | 2023
REPOSITORIES: biostudies-literature
Lee Brian N BN Wang Junwen J Nho Kwangsik K Saykin Andrew J AJ Shen Li L
AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science 20230616
Alzheimer's Disease (AD) is a highly heritable neurodegenerative disorder characterized by memory impairments. Understanding how genetic factors contribute to AD pathology may inform interventions to slow or prevent the progression of AD. We performed stratified genetic analyses of 1,574 Alzheimer's Disease Neuroimaging Initiative (ADNI) participants to examine associations between levels of quantitative traits (QT's) and future diagnosis. The Chow test was employed to determine if an individual ...[more]