A bacteriophage cocktail delivered in feed significantly reduced Salmonella colonization in challenged broiler chickens.

ABSTRACT: Nontyphoidal Salmonella spp. are a leading cause of human gastrointestinal infections and are commonly transmitted via the consumption of contaminated meat. To limit the spread of Salmonella and other food-borne pathogens in the food chain, bacteriophage (phage) therapy could be used during rearing or pre-harvest stages of animal production. This study was conducted to determine if a phage cocktail delivered in feed is capable of reducing Salmonella colonization in experimentally challenged chickens and to determine the optimal phage dose. A total of 672 broilers were divided into six treatment groups T1 (no phage diet and unchallenged); T2 (phage diet 10⁶ PFU/day); T3 (challenged group); T4 (phage diet 10⁵ PFU/day and challenged); T5 (phage diet

SUBMITTER: Thanki AM 

PROVIDER: S-EPMC10283443 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature