Health economic evaluation of nation-wide screening programmes for atrial fibrillation in the Netherlands.

ABSTRACT:

Aims

Screening for atrial fibrillation (AF) is recommended by the European Society of Cardiology guidelines to prevent strokes. Cost-effectiveness analyses of different screening programmes for AF are difficult to compare because of varying settings and models used. We compared the impact and cost-effectiveness of various AF screening programmes in the Netherlands.

Methods and results

The base case economic analysis was conducted from the societal perspective. Health effects and costs were analysed using a Markov model. The main model inputs were derived from the ARISTOTLE, RE-LY, and ROCKET AF trials combined with Dutch observational data. Univariate, probabilistic sensitivity, and various scenario analyses were performed. The maximum number of newly detected AF patients in

SUBMITTER: van Hulst M 

PROVIDER: S-EPMC10284264 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature