Severe coronavirus disease 2019 in pediatric solid organ transplant recipients: Big data convergence study in Korea (K-COV-N cohort).

ABSTRACT:

Objectives

The risk of severe COVID-19 in children with a solid organ transplant (SOT) is not well established. We compare the relative risk of severe COVID-19 infection between pediatric SOT and non-SOT children.

Methods

The newly constructed K-COV-N cohort (Korea Disease Control and Prevention Agency-COVID-19-National Health Insurance Service) was used. Children with COVID-19 (<18 years old) who underwent SOT between January 2008-January 2022 were included. Non-SOT children with COVID-19 were selected in a ratio of 1:4 using propensity score matching. Three definitions of severe COVID-19 were established based on their requirement of respiratory support: Severe I (requiring respiratory support above a high-flow nasal cannula or prolonged hospitalization ≥6 days), Severe II

SUBMITTER: Kang JM 

PROVIDER: S-EPMC10284429 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature