Prognostic value of respiratory compliance course on mortality in COVID-19 patients with vv-ECMO.

ABSTRACT:

Background

COVID-19-associated acute respiratory distress syndrome (ARDS) supported by veno-venous extra-corporal membrane oxygenation (vv-ECMO) results in a high in-hospital mortality rate of more than 35%. However, after cannulation, no prognostic factor has been described to guide the management of these patients. The objective was to assess the association between static respiratory compliance over the first 10 days post-vv-ECMO implantation on 180-day mortality.

Results

In this multicentric retrospective study in three ECMO referral centers, all patients with COVID-19-associated ARDS supported by vv-ECMO were included from 03/01/2020 to 12/31/2021. Patients were ventilated with ultra-protective settings targeting a driving pressure lower than 15 cmH₂O. 122 pa

SUBMITTER: Valentin S 

PROVIDER: S-EPMC10284783 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature