First-in-Human Safety Study of Femtosecond Laser Image-Guided Trabeculotomy for Glaucoma Treatment: 24-month Outcomes.

ABSTRACT:

Purpose

Pilot study to evaluate adverse events and intraocular pressure (IOP)-lowering of a novel, noninvasive glaucoma procedure, femtosecond laser, image-guided, high-precision trabeculotomy (FLIGHT).

Design

Prospective, nonrandomized, single-center, interventional, single-arm clinical trial.

Participants

Eighteen eyes from 12 patients with open-angle glaucoma.

Methods

Eighteen eyes from 12 patients underwent FLIGHT, creating a single channel measuring 500-μm wide by 200-μm high through the trabecular meshwork and into Schlemm's canal. Adverse events, IOP, and other parameters were evaluated out to 24 months.

Main outcome measures

Outcomes were the rates and types of adverse events and the rate of postprocedure best-corrected visual acuity loss (≥ 2 li

SUBMITTER: Nagy ZZ 

PROVIDER: S-EPMC10285639 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature