Vincristine-Induced Acrocyanosis and Erythema Pernio.

ABSTRACT:

Introduction

Acrocyanosis and erythema pernio are 2 dermatologic manifestations of vasospastic changes. Primary care providers should consider that these conditions can occur as primary or idiopathic conditions and as secondary conditions related to another disease or medication. Herein we describe a case of acrocyanosis and erythema pernio attributed to vincristine therapy.

Case description

A 22-year-old man was evaluated for discomfort and red lesions involving the toes of both feet for several weeks. He had completed chemotherapy 1 month earlier for Ewing sarcoma in the right femur. Local control for the primary tumor included wide local excision and reconstruction with a vascularized fibular allograft from the right fibula. On examination, his right foot was dark blue an

SUBMITTER: Middleton HT 

PROVIDER: S-EPMC10286157 | biostudies-literature | 2023 Jan-Dec

REPOSITORIES: biostudies-literature