Omnipresence of the sensorimotor-association axis topography in the human connectome.

ABSTRACT: Low-dimensional representations are increasingly used to study meaningful organizational principles within the human brain. Most notably, the sensorimotor-association axis consistently explains the most variance in the human connectome as its so-called principal gradient, suggesting that it represents a fundamental organizational principle. While recent work indicates these low dimensional representations are relatively robust, they are limited by modeling only certain aspects of the functional connectivity structure. To date, the majority of studies have restricted these approaches to the strongest connections in the brain, treating weaker or negative connections as noise despite evidence of meaningful structure among them. The present work examines connectivity gradients of the human con

SUBMITTER: Nenning KH 

PROVIDER: S-EPMC10286236 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature