Attenuated Total Reflection Fourier Transform Infrared Spectroscopy for Forensic Screening of Long-Term Alcohol Consumption from Human Nails.

ABSTRACT: Fourier transform infrared (FT-IR) spectroscopy is used throughout forensic laboratories for many applications. FT-IR spectroscopy can be useful with ATR accessories in forensic analysis for several reasons. It provides excellent data quality combined with high reproducibility, with minimal user-induced variations and no sample preparation. Spectra from heterogeneous biological systems, including the integumentary system, can be associated with hundreds or thousands of biomolecules. The nail matrix of keratin possesses a complicated structure with captured circulating metabolites whose presence may vary in space and time depending on context and history. We developed a new approach by using machine-learning (ML) tools to leverage the potential and enhance the selectivity of the instrument,

SUBMITTER: Mitu B 

PROVIDER: S-EPMC10286297 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature