The impact of task context on predicting finger movements in a brain-machine interface.

ABSTRACT: A key factor in the clinical translation of brain-machine interfaces (BMIs) for restoring hand motor function will be their robustness to changes in a task. With functional electrical stimulation (FES) for example, the patient's own hand will be used to produce a wide range of forces in otherwise similar movements. To investigate the impact of task changes on BMI performance, we trained two rhesus macaques to control a virtual hand with their physical hand while we added springs to each finger group (index or middle-ring-small) or altered their wrist posture. Using simultaneously recorded intracortical neural activity, finger positions, and electromyography, we found that decoders trained in one context did not generalize well to other contexts, leading to significant increases in predicti

SUBMITTER: Mender MJ 

PROVIDER: S-EPMC10287157 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature