Childhood sexual abuse is associated with higher total ghrelin serum levels in adulthood: results from a large, population-based study.

ABSTRACT: Ghrelin is an orexigenic peptide hormone synthesized in times of stress and hunger and alterations of the ghrelin system following acute stressors could be repeatedly shown in humans. However, little data exists on long-term effects of trauma on the ghrelin system. We aimed to investigate the influence of childhood trauma on total ghrelin serum levels in a large, population-based study. Total serum ghrelin was measured in 1666 participants of a population-based cross-sectional study ('LIFE study'). The Childhood Trauma Screener (CTS) was used for the assessment of childhood trauma in the final sample (n = 1086; mean age: 57.10 ± 16.23 years; 632 males, 454 females). Multiple linear regression analyses and generalized linear models were chosen to examine the association between childhood tr

SUBMITTER: Wittekind DA 

PROVIDER: S-EPMC10287627 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature