Farm biosecurity measures to prevent hepatitis E virus infection in finishing pigs on endemically infected pig farms.

ABSTRACT: Hepatitis E virus (HEV) can be transmitted from pigs to humans and cause liver inflammation. Pigs are a major reservoir of HEV and most slaughter pigs show evidence of infection by presence of antibodies (ELISA) or viral RNA (PCR). Reducing the number of HEV infected pigs at slaughter would likely reduce human exposure, yet how this can be achieved, is unknown. We aimed to identify and quantify the effect of biosecurity measures to deliver HEV negative batches of pigs to slaughter. A case-control study was performed with Dutch pig farms selected based on results of multiple slaughter batches. Case farms delivered at least one PCR and ELISA negative batch to slaughter (PCR^-ELISA^-), indicating absence of HEV infection, and control farms had the highest proportion of PCR

SUBMITTER: Meester M 

PROVIDER: S-EPMC10288132 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature