Primary intracranial sarcomas: a clinicopathological investigation.

ABSTRACT:

Background

The purpose of this study is to present a series of primary intracranial sarcomas (PIS), a rare type of tumor of the central nervous system, in order to improve our understanding of the disease. These tumors are heterogeneous and prone to recurrence after resection, exhibiting a high mortality rate. As PIS has yet to be understood and studied on a large scale, it is vital for further evaluation and research.

Methods

Our study included 14 cases of PIS. The patients' clinical, pathological, and imaging features were retrospectively analyzed. Additionally, targeted DNA next-generation sequencing (NGS) was applied for the 481-gene panel to detect gene mutations.

Results

The average age for PIS patients was 31.4 years. Headache (7, 50.0%) was the most common sym

SUBMITTER: Cai YX 

PROVIDER: S-EPMC10288519 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature