Electrochemical Detection of Borrelia burgdorferi Using a Biomimetic Flow Cell System.

ABSTRACT: Lyme disease, caused by infection with pathogenic Borrelia bacteria, has emerged as a pervasive illness throughout North America and many other regions of the world in recent years, owing in part to climate-mediated habitat expansion of the tick vectors. Standard diagnostic testing has remained largely unchanged over the past several decades and is indirect, relying on detection of antibodies against the Borrelia pathogen, rather than detection of the pathogen itself. The development of new rapid, point-of-care tests for Lyme disease that directly detects the pathogen could drastically improve patient health by enabling faster and more frequent testing that could better inform patient treatment. Here, we describe a proof-of-concept electrochemical sensing approach to the dete

SUBMITTER: Flynn CD 

PROVIDER: S-EPMC10288608 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature