Trajectories of glycated hemoglobin of T2DM and progress of arterial stiffness: a prospective study.

ABSTRACT:

Aim

This study aimed to describe the different trajectories groups of HbA1c during the long-term treatment of diabetes and explore the effect of glycemic control on the progression of arterial stiffness.

Method

The study participants registered at the National Metabolic Management Center (MMC) of Beijing Luhe hospital. The latent class mixture model (LCMM) was used to identify distinct trajectories of HbA1c. We calculated the change value of baPWV (ΔbaPWV) of each participant between the whole follow-up time as the primary outcome. Then we examined the associations between each HbA1c trajectory pattern and ΔbaPWV using covariate-adjusted means (SE) of ΔbaPWV, which were calculated by multiple linear regression analyses adjusted for the covariates.

Results

After data c

SUBMITTER: Li K 

PROVIDER: S-EPMC10288736 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature