Treatment and outcome of hepatorenal syndrome in Japan: a retrospective cohort study using a national inpatient database.

ABSTRACT:

Background

Hepatorenal syndrome (HRS) is a life-threatening complication of end-stage liver disease. This study aimed to clarify the status of HRS in Japan by analyzing the Japanese Diagnosis Procedure Combination database.

Methods

Patients hospitalized for cirrhosis and HRS from July 2010 to March 2019 were sampled. They were divided into two groups according to their prognosis upon discharge: the transplant-free survival group and the death or liver transplantation group. The two groups' baseline patient characteristics and treatments were compared.

Results

The mean age of the 1,412 participants was 67.3 years (standard deviation: 12.3 years), and 65.4% were male. The Child-Pugh grades was B and C in 18.8% and 81.2%, respectively. Hepatocellular carcinoma was presen

SUBMITTER: Okushin K 

PROVIDER: S-EPMC10288750 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature