Inflammation in stroke: initial CRP levels can predict poor outcomes in endovascularly treated stroke patients.

ABSTRACT:

Background and purpose

Inflammation has been linked to poor prognoses in cardio- and cerebrovascular conditions. As it is known to increase after ischemia, C-reactive protein (CRP) may serve as a surrogate for systemic inflammation and thus be a hallmark of increased tissue vulnerability. The question arises whether CRP in the acute phase of ischemic stroke, prior to mechanical thrombectomy (MT), might help predict outcomes.

Materials and methods

A single-center collective of patients with large-vessel occlusion, who were treated via MT, was analyzed in this observational case-control study. Univariate and multivariate models were designed to test the prognostic value of inflammatory markers (CRP and leukocytosis) in predicting clinical outcomes (modified Rankin score >2) an

SUBMITTER: Finck T 

PROVIDER: S-EPMC10289003 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature