Erythrocyte Membrane Fatty Acid Composition as a Potential Biomarker for Depression.

ABSTRACT:

Background

Major depressive disorders is a chronic and severe psychiatric disorder with poor prognosis and quality of life. Abnormal erythrocyte fatty acid (FA) composition in depressed patients were found in our previous study, but the relationship between erythrocyte membrane FA levels and different severity of depressive and anxiety symptoms remains to be explored.

Methods

This cross-sectional study included 139 patients with first-diagnosed, drug-naïve depression and 55 healthy controls whose erythrocyte FA composition was analyzed. Patients with depression were divided into severe depression and mild to moderate depression or depression with severe anxiety and mild to moderate anxiety. Then the differences of FA levels among different groups were analyzed. Finally, the

SUBMITTER: Liu T 

PROVIDER: S-EPMC10289140 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature