A negative association between triglyceride glucose-body mass index and testosterone in adult males: a cross-sectional study.

ABSTRACT:

Background and objectives

Insulin resistance (IR) is closely related to the decline or deficiency of testosterone in males. Triglyceride glucose-body mass (TyG-BMI) is considered to be a novel indicator of IR. We conducted this analysis to investigate the association between TyG-BMI and male testosterone, and to explore whether its ability to predict testosterone deficiency is superior to HOMA-IR and TyG.

Methods

This was a cross-sectional study using data from the National Health and Nutrition Examination Survey (NHANES, 2011-2016). The TyG-BMI index was calculated from serum triglyceride, fasting plasma glucose and BMI. The association of TyG-BMI with male testosterone was estimated by weighted multivariable regression.

Results

We included 3394 participants for the

SUBMITTER: Wu S 

PROVIDER: S-EPMC10289259 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature