Investigating the association between neoplasms and MOG antibody-associated disease.

ABSTRACT:

Introduction

The association of myelin oligodendrocyte glycoprotein (MOG) antibody associated disease (MOGAD) and tumors has seldom been reported. We aim to investigate the occurrence of tumors in a cohort of patients with MOGAD and to describe their clinical features, in addition to previously reported cases.

Methods

We retrospectively identified patients with MOGAD (i.e., compatible clinical phenotype and positive MOG antibodies analysed with a live cell-based assay) from 1/1/2015 to 1/1/2023 who had a neoplasm diagnosed within 2  years from MOGAD onset. Furthermore, we performed systematic review of literature to identify previously reported cases. Clinical, paraclinical and oncological findings were collected and reported as median (range) or number (percentage).

Resu

SUBMITTER: Trentinaglia M 

PROVIDER: S-EPMC10289293 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature