Multiple system atrophy with oculomotor abnormalities as a prominent manifestation: A case series.

ABSTRACT:

Rationale

Multiple system atrophy (MSA) is a group of adult-onset sporadic neurodegenerative diseases, mainly classified as MSA-C and MSA-P types. Due to the diversity of clinical symptoms, diagnosis faces a significant challenge. In the present case, we report a patient with isolated vertigo as the first presentation and abnormalities of the oculomotor system as the characteristic manifestations.

Case concern

A 64-year-old male had dizziness for 1 year, aggravated for 4 months, with accompanying symptoms of unsteady walking. Physical examination revealed spontaneous nystagmus, abnormal ataxic movements, and a broad basal gait. Video nystagmography revealed saccade intrusions and macrosaccadic oscillations, and opsoclonus. Magnetic resonance imaging (MRI) was unremarkable ea

SUBMITTER: Wei Y 

PROVIDER: S-EPMC10289487 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature