Phantom-based radiomics feature test-retest stability analysis on photon-counting detector CT.

ABSTRACT:

Objectives

Radiomics image data analysis offers promising approaches in research but has not been implemented in clinical practice yet, partly due to the instability of many parameters. The aim of this study is to evaluate the stability of radiomics analysis on phantom scans with photon-counting detector CT (PCCT).

Methods

Photon-counting CT scans of organic phantoms consisting of 4 apples, kiwis, limes, and onions each were performed at 10 mAs, 50 mAs, and 100 mAs with 120-kV tube current. The phantoms were segmented semi-automatically and original radiomics parameters were extracted. This was followed by statistical analysis including concordance correlation coefficients (CCC), intraclass correlation coefficients (ICC), as well as random forest (RF) analysis, and cluster a

SUBMITTER: Hertel A 

PROVIDER: S-EPMC10289937 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature