Ontology highlight
ABSTRACT:
SUBMITTER: Li J
PROVIDER: S-EPMC10290152 | biostudies-literature | 2023 Jun
REPOSITORIES: biostudies-literature
Li Jing J Huang Qi Q Lv Minling M Ma Wenfeng W Sun Jialing J Zhong Xin X Hu Rui R Ma MengQing M Han Zhiyi Z Zhang Wei W Feng Wenxing W Sun Xinfeng X Zhou Xiaozhou X
Cell death discovery 20230623 1
Acute liver injury (ALI) is an acute inflammatory liver disease with a high mortality rate. Alternatively, activated macrophages (AAMs) have been linked to the inflammation and recovery of ALI. However, the mechanism underlying AAM death in ALI has not been studied sufficiently. We used liensinine (Lie) as a drug of choice after screening a library of small-molecule monomers with 1488 compounds from traditional Chinese remedies. In ALI, we evaluated the potential therapeutic effects and underlyi ...[more]