PPIntegrator: semantic integrative system for protein-protein interaction and application for host-pathogen datasets.

ABSTRACT:

Summary

Semantic web standards have shown importance in the last 20 years in promoting data formalization and interlinking between the existing knowledge graphs. In this context, several ontologies and data integration initiatives have emerged in recent years for the biological area, such as the broadly used Gene Ontology that contains metadata to annotate gene function and subcellular location. Another important subject in the biological area is protein-protein interactions (PPIs) which have applications like protein function inference. Current PPI databases have heterogeneous exportation methods that challenge their integration and analysis. Presently, several initiatives of ontologies covering some concepts of the PPI domain are available to promote interoperability across datas

SUBMITTER: Martins YC 

PROVIDER: S-EPMC10290227 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature