Association of Size Matching Using Predicted Heart Mass With Mortality in Heart Transplant Recipients With Obesity or High Pulmonary Vascular Resistance.

ABSTRACT:

Importance

Pretransplant obesity and higher pulmonary vascular resistance (PVR) are risk factors for death after heart transplant. However, it remains unclear whether appropriate donor-to-recipient size matching using predicted heart mass (PHM) is associated with lower risk.

Objective

To investigate the association of size matching using PHM with risk of death posttransplant among patients with obesity and/or higher PVR.

Design, setting, and participants

All adult patients (>18 years) who underwent heart transplant between 2003 and 2022 with available information using the United Network for Organ Sharing cohort database. Multivariable Cox models and multivariable-adjusted spline curves were used to examine the risk of death posttransplant with PHM matching. Data were

SUBMITTER: Tao R 

PROVIDER: S-EPMC10290246 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature