A new dyslipidemia-based scoring model to predict transplant-free survival in patients with hepatitis E-triggered acute-on-chronic liver failure.

ABSTRACT:

Background/aims

Hepatitis E virus (HEV)-triggered acute-on-chronic liver failure (ACLF) has unacceptably high short-term mortality. However, it is unclear whether the existing predictive scoring models are applicable to evaluate the prognosis of HEV-triggered ACLF.

Methods

We screened datasets of patients with HEV-triggered ACLF from a regional tertiary hospital for infectious diseases in Shanghai, China, between January 2011 and January 2021. Clinical and laboratory parameters were recorded and compared to determine a variety of short-term mortality risk factors, which were used to develop and validate a new prognostic scoring model.

Results

Out of 4952 HEV-infected patients, 817 patients with underlying chronic liver disease were enrolled in this study. Among these,

SUBMITTER: Chen C 

PROVIDER: S-EPMC10290386 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature