Cost-Effectiveness of Colchicine for Recurrent Cardiovascular Events.

ABSTRACT:

Background

Colchicine is an anti-inflammatory therapy with a low associated cost that has been shown in 2 large studies to reduce cardiovascular (CV) events, but its use is associated with side effects. The main objective for this analysis is to determine whether colchicine therapy is cost-effective for the prevention of recurrent CV events in patients who have suffered a myocardial infarction (MI).

Methods

A decision model was developed to estimate the healthcare costs in Canadian dollars and the clinical outcomes among patients who have suffered an MI and are treated with colchicine. Probabilistic Markov modelling was used in combination with Monte Carlo simulation to derive expected lifetime costs and quality-adjusted life-years, which permitted the calculation of increme

SUBMITTER: Boczar KE 

PROVIDER: S-EPMC10290950 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature