Effect of pre-operative radiation therapy on surgical outcome in retroperitoneal sarcoma.

ABSTRACT:

Background

A high rate of locoregional recurrence is one of the major difficulties in successful treatment of retroperitoneal sarcoma (RPS). Although pre-operative radiation therapy (RT) is considered a potential way to improve local recurrence, concerns about the associated treatment toxicity and risk of peri-operative complications need to be addressed. Hence, this study investigates the safety of pre-operative RT (preRTx) for RPS.

Methods

A cohort of 198 patients with RPS who had undergone both surgery and RT was analyzed for peri-operative complications. They were divided into three groups according to the RT scheme: (1) preRTx group, (2) post-operative RT without tissue expander, and (3) post-operative RT with tissue expander.

Results

The preRTx was overall well

SUBMITTER: Jo SJ 

PROVIDER: S-EPMC10291121 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature