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Distinct Reactivity Modes of a Copper Hydride Enabled by an Intramolecular Lewis Acid.

ABSTRACT: We disclose a 1,4,7-triazacyclononane (TACN) ligand featuring an appended boron Lewis acid. Metalation with Cu(I) affords a series of tetrahedral complexes including a boron-capped cuprous hydride. We demonstrate distinct reactivity modes as a function of chemical oxidation: hydride transfer to CO₂ in the copper(I) state and oxidant-induced H₂ evolution as well as alkyne reduction.

SUBMITTER: Norwine EE

PROVIDER: S-EPMC10291504 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature

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Distinct Reactivity Modes of a Copper Hydride Enabled by an Intramolecular Lewis Acid.

Norwine Emily E EE Kiernicki John J JJ Zeller Matthias M Szymczak Nathaniel K NK

Journal of the American Chemical Society 20220812 33

We disclose a 1,4,7-triazacyclononane (TACN) ligand featuring an appended boron Lewis acid. Metalation with Cu(I) affords a series of tetrahedral complexes including a boron-capped cuprous hydride. We demonstrate distinct reactivity modes as a function of chemical oxidation: hydride transfer to CO<sub>2</sub> in the copper(I) state and oxidant-induced H<sub>2</sub> evolution as well as alkyne reduction. ...[more]

PMID: 35960993

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