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Muller Glia to Muller Glia Extracellular Vesicle-Dependent Signaling Induces Multipotency Genes Nestin and lin28 Expression in Response to N-methyl-D-aspartate (NMDA) Exposure.


ABSTRACT:

Summary statement

Retinal Müller cells secrete extracellular vesicles that can be captured by other Müller cells. In response to a signal that may be deleterious for the retina, Müller glia-derived extracellular vesicles spread instructions to induce gene expression changes in other cells.

SUBMITTER: Carapia AK 

PROVIDER: S-EPMC10291543 | biostudies-literature | 2023 Jan-Dec

REPOSITORIES: biostudies-literature

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Müller Glia to Müller Glia Extracellular Vesicle-Dependent Signaling Induces Multipotency Genes <i>Nestin</i> and l<i>in28</i> Expression in Response to N-methyl-D-aspartate (NMDA) Exposure.

Carapia Ana Karen AK   Martinez-Colin Erick J EJ   Segura-Villalobos Deisy D   Victoria-Chavez Rebeca Yael RY   Lezama Ivonne I   Martinez-Martinez Eduardo E   Lamas Monica M  

ASN neuro 20230101


<h4>Summary statement</h4>Retinal Müller cells secrete extracellular vesicles that can be captured by other Müller cells. In response to a signal that may be deleterious for the retina, Müller glia-derived extracellular vesicles spread instructions to induce gene expression changes in other cells. ...[more]

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