Noise, Air, and Heavy Metal Pollution as Risk Factors for Endothelial Dysfunction.

ABSTRACT: During the last two decades, large epidemiological studies have shown that the physical environment, including noise, air pollution or heavy metals, have a considerable impact on human health. It is known that the most common cardiovascular risk factors are all associated with endothelial dysfunction. Vascular tone, circulation of blood cells, inflammation, and platelet activity are some of the most essential functions regulated by the endothelium that suffer negative effects as a consequence of environmental pollution, causing endothelial dysfunction. In this review, we delineate the impact of environmental risk factors in connection to endothelial function. On a mechanistic level, a significant number of studies suggest the involvement of endothelial dysfunction to fundamentally drive th

SUBMITTER: Bayo Jimenez MT 

PROVIDER: S-EPMC10291605 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature