Case report: Improvement in refractory functional seizures, depression, and quality of life with ketamine-assisted therapy.

ABSTRACT: Functional seizures, a primary subtype of functional neurological disorder (FND), are a known cause of serious neurological disability with an increasing awareness of their impact amongst the neuroscience community. Situated at the intersection of neurology and psychiatry, FND is characterized by a range of alterations in motor, sensory or cognitive performance, such as abnormal movements, limb weakness, and dissociative, seizure-like episodes. Functional seizures are known, in part, to have psychological underpinnings; however, the lack of effective and consistent treatment options requires research and novel approaches to better understand the etiology, diagnosis and what constitutes a successful intervention. Ketamine, a selective blocker of the N-methyl-D-aspartate receptor, has a well

SUBMITTER: Argento E 

PROVIDER: S-EPMC10291615 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature