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Endocrine Complications of Cystic Fibrosis.


ABSTRACT: Endocrine comorbidities have become increasingly important medical considerations as improving cystic fibrosis (CF) care increases life expectancy. Although the underlying pathophysiology of CF-related diabetes remains elusive, the use of novel technologies and therapeutics seeks to improve both CF-related outcomes and quality of life. Improvements in the overall health of those with CF have tempered concerns about pubertal delay and short stature; however, other comorbidities such as hypogonadism and bone disease are increasingly recognized. Following the introduction of highly effective modulator therapies there are many lessons to be learned about their long-term impact on endocrine comorbidities.

SUBMITTER: Kelly A 

PROVIDER: S-EPMC10291706 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature

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Endocrine Complications of Cystic Fibrosis.

Kelly Andrea A   Marks Brynn E BE   Stalvey Michael S MS  

Clinics in chest medicine 20221201 4


Endocrine comorbidities have become increasingly important medical considerations as improving cystic fibrosis (CF) care increases life expectancy. Although the underlying pathophysiology of CF-related diabetes remains elusive, the use of novel technologies and therapeutics seeks to improve both CF-related outcomes and quality of life. Improvements in the overall health of those with CF have tempered concerns about pubertal delay and short stature; however, other comorbidities such as hypogonadi  ...[more]

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