The microbiota of pregnant women with SARS-CoV-2 and their infants.

ABSTRACT:

Background

Infants receive their first bacteria from their birthing parent. This newly acquired microbiome plays a pivotal role in developing a robust immune system, the cornerstone of long-term health.

Results

We demonstrated that the gut, vaginal, and oral microbial diversity of pregnant women with SARS-CoV-2 infection is reduced, and women with early infections exhibit a different vaginal microbiota composition at the time of delivery compared to their healthy control counterparts. Accordingly, a low relative abundance of two Streptococcus sequence variants (SV) was predictive of infants born to pregnant women with SARS-CoV-2 infection.

Conclusions

Our data suggest that SARS-CoV-2 infections during pregnancy, particularly early infections, are associated with lasti

SUBMITTER: Leftwich HK 

PROVIDER: S-EPMC10291758 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature