Predictive value of albumin for intravenous immunoglobulin resistance in a large cohort of Kawasaki disease patients.

ABSTRACT:

Background

Intravenous immunoglobulin (IVIG) has been the mainstay of treatment for Kawasaki disease (KD) over the past decades. However, 10-20% of KD patients are resistant to IVIG treatment which puts those patients at high risk of coronary artery lesions (CALs). Therefore, it is important to predict whether patients will be resistant to IVIG before the treatment. This study aimed to investigate the risk factors for IVIG non-responsive patients with KD.

Methods

This study enrolled patients diagnosed with KD and divided them into two groups, IVIG responders and IVIG non-responders. We compared the differences in demographics and clinical data between the two groups. Differences among the groups were analyzed by ANOVA and Chi-square analysis. Predictors of IVIG resistance we

SUBMITTER: Zhang R 

PROVIDER: S-EPMC10291809 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature