A prospective cohort study of infertility and cancer incidence.

ABSTRACT:

Objective

To investigate the association between infertility and the incidence of invasive cancer.

Design

Prospective cohort study (1989-2015).

Setting

Not applicable.

Patient(s)

A total of 103,080 women aged 25-42 years in the Nurses' Health Study II who were cancer-free at baseline (1989).

Intervention(s)

The infertility status (failure to conceive after 1 year of regular, unprotected sex) and causes of infertility were self-reported at baseline and biennial follow-up questionnaires.

Main outcome measure(s)

Cancer diagnosis was confirmed through medical record review and classified as obesity-related (colorectal, gallbladder, kidney, multiple myeloma, thyroid, pancreatic, esophageal, gastric, liver, endometrial, ovarian, and postmenopausal breas

SUBMITTER: Wang S 

PROVIDER: S-EPMC10293067 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature