Discovery of long non-coding RNAs in Aspergillus flavus response to water activity, CO₂ concentration, and temperature changes.

ABSTRACT: Although the role of long non-coding RNAs (lncRNAs) in key biological processes in animals and plants has been confirmed for decades, their identification in fungi remains limited. In this study, we discovered and characterized lncRNAs in Aspergillus flavus in response to changes in water activity, CO₂ concentration, and temperature, and predicted their regulatory roles in cellular functions. A total of 472 lncRNAs were identified in the genome of A. flavus, consisting of 470 novel lncRNAs and 2 putative lncRNAs (EFT00053849670 and EFT00053849665). Our analysis of lncRNA expression revealed significant differential expression under stress conditions in A. flavus. Our findings indicate that lncRNAs in A. flavus, particularly down-regulated lncRNAs, may play pivotal regulatory rol

SUBMITTER: Davati N 

PROVIDER: S-EPMC10293223 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature