Dataset Information

Neo4j graph dataset of cycling paths in Slovenia.

ABSTRACT: Navigating through a real-world map can be represented in a bi-directed graph with a group of nodes representing the intersections and edges representing the roads between them. In cycling, we can plan training as a group of nodes and edges the athlete must cover. Optimizing routes using artificial intelligence is a well-studied phenomenon. Much work has been done on finding the quickest and shortest paths between two points. In cycling, the solution is not necessarily the shortest and quickest path. However, the optimum path is the one where a cyclist covers the suitable distance, ascent, and descent based on his/her training parameters. This paper presents a Neo4j graph-based dataset of cycling routes in Slovenia. It consists of 152,659 nodes representing individual road intersections and 410,922 edges representing the roads between them. The dataset allows the researchers to develop and optimize cycling training generation algorithms, where distance, ascent, descent, and road type are considered.

SUBMITTER: Rajsp A

PROVIDER: S-EPMC10293952 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature

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Neo4j graph dataset of cycling paths in Slovenia.

Rajšp Alen A Fister Iztok I

Data in brief 20230527

Navigating through a real-world map can be represented in a bi-directed graph with a group of nodes representing the intersections and edges representing the roads between them. In cycling, we can plan training as a group of nodes and edges the athlete must cover. Optimizing routes using artificial intelligence is a well-studied phenomenon. Much work has been done on finding the quickest and shortest paths between two points. In cycling, the solution is not necessarily the shortest and quickest ...[more]

PMID: 37383783

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Project description:BackgroundMany studies prove that miRNAs have significant roles in diagnosing and treating complex human diseases. However, conventional biological experiments are too costly and time-consuming to identify unconfirmed miRNA-disease associations. Thus, computational models predicting unidentified miRNA-disease pairs in an efficient way are becoming promising research topics. Although existing methods have performed well to reveal unidentified miRNA-disease associations, more work is still needed to improve prediction performance.ResultsIn this work, we present a novel multiple meta-paths fusion graph embedding model to predict unidentified miRNA-disease associations (M2GMDA). Our method takes full advantage of the complex structure and rich semantic information of miRNA-disease interactions in a self-learning way. First, a miRNA-disease heterogeneous network was derived from verified miRNA-disease pairs, miRNA similarity and disease similarity. All meta-path instances connecting miRNAs with diseases were extracted to describe intrinsic information about miRNA-disease interactions. Then, we developed a graph embedding model to predict miRNA-disease associations. The model is composed of linear transformations of miRNAs and diseases, the means encoder of a single meta-path instance, the attention-aware encoder of meta-path type and attention-aware multiple meta-path fusion. We innovatively integrated meta-path instances, meta-path based neighbours, intermediate nodes in meta-paths and more information to strengthen the prediction in our model. In particular, distinct contributions of different meta-path instances and meta-path types were combined with attention mechanisms. The data sets and source code that support the findings of this study are available at https://github.com/dangdangzhang/M2GMDA .ConclusionsM2GMDA achieved AUCs of 0.9323 and 0.9182 in global leave-one-out cross validation and fivefold cross validation with HDMM V2.0. The results showed that our method outperforms other prediction methods. Three kinds of case studies with lung neoplasms, breast neoplasms, prostate neoplasms, pancreatic neoplasms, lymphoma and colorectal neoplasms demonstrated that 47, 50, 49, 48, 50 and 50 out of the top 50 candidate miRNAs predicted by M2GMDA were validated by biological experiments. Therefore, it further confirms the prediction performance of our method.

Dataset Information

Neo4j graph dataset of cycling paths in Slovenia.

Publications

Neo4j graph dataset of cycling paths in Slovenia.

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