Short-Course Therapy for Urinary Tract Infections in Children: The SCOUT Randomized Clinical Trial.

ABSTRACT:

Importance

There is a paucity of pediatric-specific comparative data to guide duration of therapy recommendations in children with urinary tract infection (UTI).

Objective

To compare the efficacy of standard-course and short-course therapy for children with UTI.

Design, setting, participants

The Short Course Therapy for Urinary Tract Infections (SCOUT) randomized clinical noninferiority trial took place at outpatient clinics and emergency departments at 2 children's hospitals from May 2012, through, August 2019. Data were analyzed from January 2020, through, February 2023. Participants included children aged 2 months to 10 years with UTI exhibiting clinical improvement after 5 days of antimicrobials.

Intervention

Another 5 days of antimicrobials (standard-cours

SUBMITTER: Zaoutis T 

PROVIDER: S-EPMC10294016 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature