Selection signature analysis reveals RDH5 performed key function in vision during sheep domestication process.

ABSTRACT: As one of the most successful domesticated animals in the Neolithic age, sheep gradually migrated all over the world with human activities. During the domestication process, remarkable changes have taken place in morphology, physiology, and behavior, resulting in different breeds with different characters via artificial and natural selection. However, the genetic background responsible for these phenotypic variations remains largely unclear. Here, we used whole genome resequencing technology to compare and analyze the genome differences between Asiatic mouflon wild sheep (Ovis orientalis) and Hu sheep (Ovis aries). A total of 755 genes were positively selected in the process of domestication and selection, and the genes related to sensory perception had directional evolution

SUBMITTER: Hu R 

PROVIDER: S-EPMC10294028 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature