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Towards long double-stranded chains and robust DNA-based data storage using the random code system.


ABSTRACT: DNA has become a popular choice for next-generation storage media due to its high storage density and stability. As the storage medium of life's information, DNA has significant storage capacity and low-cost, low-power replication and transcription capabilities. However, utilizing long double-stranded DNA for storage can introduce unstable factors that make it difficult to meet the constraints of biological systems. To address this challenge, we have designed a highly robust coding scheme called the "random code system," inspired by the idea of fountain codes. The random code system includes the establishment of a random matrix, Gaussian preprocessing, and random equilibrium. Compared to Luby transform codes (LT codes), random code (RC) has better robustness and recovery ability of lost in

SUBMITTER: Yang X 

PROVIDER: S-EPMC10294226 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature